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All About Triglycerides


By Pat Kendall, Ph.D., R.D.
Food Science and Human Nutrition Specialist
Colorado State University Extension
October 8, 1997
 

Just when you start feeling comfortable about cholesterol--what it is, where it comes from, the difference between high density lipoproteins (HDL), the good stuff, and low density lipoproteins (LDL), the not-so-good stuff, you start hearing about these things called triglycerides.

Actually, triglycerides have been reported on blood tests for years. Doctors used to place just as much emphasis on them as they did cholesterol when assessing a person's risk for heart disease. However, when we learned enough about cholesterol to consider it an independent risk factor for heart disease at levels above 240 milligrams per deciliter (mg/dl), most eyes focused on cholesterol.

High triglyceride levels also are a factor in heart disease risk, but how and at what levels remains less clear. Research findings have been mixed. The Framingham Heart Study found a significant increase in coronary artery disease in women with high triglycerides independent of other lipid abnormalities. However, other studies have found an elevated risk only when high triglycerides occur with decreased HDL levels.

Just what are triglycerides? The term is simply a fancy name for fat, or what scientists call lipids. More than 90 percent of the fat in the food we eat and in the fat folds on our bodies is made up of triglycerides. The other two main classes of fats are phospholipids, such as lecithin, and sterols, such as cholesterol.

Like cholesterol, triglycerides are a necessary component of our body chemistry. Triglycerides circulate constantly in the blood, ferrying fat-soluble vitamins A, D, E and K to locations where they're needed, aiding in the synthesis of certain hormones and protecting cell membranes. Unlike cholesterol, triglyceride particles are large and do not enter the blood vessels and contribute to arterial blockages in the same way cholesterol does. Still, high triglyceride levels do indicate a defect in the system and may be an early warning of heart trouble.

The lab test to measure blood triglyceride levels is easy and usually can be done along with a routine cholesterol screen. Traditionally, levels between 200 to 400 mg/dl have been considered borderline; levels above 400 were considered high. Some specialists now believe levels above 150 mg/dl are a red flag. Triglyceride levels vary tremendously from day to day and in response to meals. Tests should be run on fasting patients, and at least two separate tests may be required to get an accurate reading.

So, what should you do if your triglyceride levels are high? Doctors should always help with the interpretation of blood tests. In general, though, the recommendations for reducing high triglyceride levels are much the same as for reducing heart disease risk. Achieve and maintain a healthy body weight, incorporate regular exercise into your daily routine and eat a low-fat diet rich in fruits, vegetables and whole grains. Also, limit refined carbohydrates like sugar and high-fructose corn syrup and consider restricting alcohol consumption, which can stimulate triglyceride production in some people.

For more information, contact your local Colorado State University Extension office.


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Updated Tuesday, November 27, 2007.

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